A giant alligator goes head to head with a giant Anaconda. The town sheriff must find a way to destroy the two monsters before they kill the whole town.

A genetically created Anaconda, cut in half, regenerates itself into two new aggressive giant snakes, due to the Blood Orchid.

A scientific expedition sets out for Borneo to seek a flower called the Blood Orchid, which could grant extended life. Meanwhile, they run afoul of snakes and each other.